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In the SURMOUNT-4 trial, 82.5% of adults with obesity regained ≥25% of initial weight lost within one year of tirzepatide withdrawal; most showed reversal of cardiometabolic improvements. https://ja.ma/4pADUmu
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Body composition changes during weight reduction with tirzepatide in the SURMOUNT‐1 study of adults with obesity or overweight - Look - 2025 - Diabetes, Obesity and Metabolism
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Tirzepatide Was Associated with Improved Health-Related Quality of Life in Adults with Obesity or Overweight and Type 2 Diabetes: Results from the Phase 3 SURMOUNT-2 Trial | Diabetes Therapy
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SURMOUNT-1: Adults achieve weight loss of 16% or more at 72 weeks with tirzepatide
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